Search on: ADAM10 PROTEIN 
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Descriptor English:   ADAM10 Protein 
Descriptor Spanish:   Proteína ADAM10 
Descriptor Portuguese:   Proteína ADAM10 
Synonyms English:   ADAM-10 Protein
CD156c Antigen
CD156w Antigen
Disintegrin and Metalloproteinase Domain-Containing Protein 10
ADAM 10 Protein
Antigen, CD156c
Antigen, CD156w
Disintegrin and Metalloproteinase Domain Containing Protein 10  
Tree Number:   D08.811.277.656.675.374.102.250
D09.400.430.500.250
D12.776.395.033.250
D23.050.301.264.035.048
D23.101.100.110.048
Definition English:   A disintegrin and metalloproteinase domain-containing protein. It cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA between ALANINE 76 and VALINE 77 to its functional form, as well as several other CELL SURFACE PROTEINS to their soluble forms, including AMYLOID BETA-PROTEIN PRECURSOR and PRION PROTEIN. 
History Note English:   2017 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   56483 
Unique Identifier:   D000072197 

Occurrence in VHL:
 

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